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Halfway by his profession, Cees Dekker reinvented himself. Immediately after a long time of hardcore physics, he shifted his aim to ‘nanobiology’ on the transform from the millennium. A expression he coined himself, as a subject of fact.

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Back in 1991, Sumio Iijima from the NEC Corporation had reported the synthesis of carbon nanotubes. Band structure calculations recommended that these nanotubes could exhibit metallic band conduction. This could be a substantial advantage more than the conducting polymers we had explored, which were, in fact, disordered semiconductors offering merely variable-range hopping conductivity.

Considering that 2000, Dekker has shifted the main target of his get the job done towards biophysics in which he scientific tests the properties of single biomolecules and cells using the instruments of nanotechnology. This change of area was pushed by his fascination with the outstanding working of Organic molecular buildings, as well as from the prolonged-expression standpoint that many fascinating discoveries might be predicted With this industry.[five] Current lines of study in his biophysics group are within the parts of:[six]

2015, discovery that condensin is really a highly versatile protein construction; and first detection of DNA knots working with nanopores

Immediate immobilization of indigenous yeast iso-1 cytochrome c on bare gold: fast electron relay to redox enzymes and zeptomole protein-movie voltammetry

MATLAB codes for details processing can be obtained at . Julia codes used for numerical simulation are offered at .

Atomic pressure microscopy reveals that vaccinia topoisomerase IB generates filaments on DNA inside a cooperative trend

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Resolving the move sizing in condensin-pushed DNA loop extrusion identifies ATP binding as being the action-making approach

‘The concept that You can find such a factor being a commencing, a huge bang, is ceesdekker.net already an interesting signpost to contemplate that there was a creator. But far more normally, and on The idea of pure rationality, I also get there in a Christian interpretation of reality. An atheistic worldview is usually a naturalistic worldview: fundamentally, you will discover only atoms and purely natural forces that we are able to evaluate.

‘That considerations the synthetic cell, as Component of the Dutch BaSyC initiative. Craig Venter looked prime-down in Those people days and determined about 5 hundred genes which are minimally essential for a working mobile. We wish to appear bottom-up: how can we shift from a handful of molecules to an entire Organic method?

2005, discovery of your mechanism of DNA uncoiling by topoisomerase enzymes; discovery of extensive-variety conformational improvements in Mre11/DNA restore complexes; and 1st drive measurements on the DNA molecule inside of a nanopore

‘I am driven by ponder and issues. On a cloth amount I discover answers in physics, but I knowledge my deepest contentment with God. That religion also drives my science and how I cope with folks.